Compound Detail
CHEMBL23929
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL23929 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UXOJFXXDDRFWJR-AWEZNQCLSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
303.4
MW (Da)
2.21
ALogP
4
HBA
2
HBD
50.7
PSA (Ų)
0.73
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.87
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-1 adrenergic receptor CHEMBL5471 | IC50 | 5.87 | 5.77 | 1350.0 | 2 |
| Adrenergic receptor beta CHEMBL2095166 | IC50 | 5.81 | 5.81 | 1540.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-1 adrenergic receptor | IC50 | = | 1350.0 | nM | 5.87 | Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit... | - |
| Adrenergic receptor beta | IC50 | = | 1540.0 | nM | 5.81 | The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol bin... | - |
| Beta-1 adrenergic receptor | IC50 | = | 2150.0 | nM | 5.67 | Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)00207-2 | Beta-1 adrenergic receptor | 2 |
| - | 10.1016/S0960-894X(97)00207-2 | Adrenergic receptor beta | 1 |
| - | 10.1016/S0960-894X(97)00207-2 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine