Compound Detail
CHEMBL2397184
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Basic Information
| ChEMBL ID | CHEMBL2397184 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RWGNJWYVGXCPEE-WYMLVPIESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
380.4
MW (Da)
4.53
ALogP
5
HBA
0
HBD
69.7
PSA (Ų)
0.28
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BV-2 CHEMBL614781 | IC50 | 5.38 | 5.38 | 4200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| BV-2 | IC50 | = | 4200.0 | nM | 5.38 | Antineuroinflammatory activity in mouse BV2 cells assessed as reduction of LPS-i... | 23726032 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23726032 | 10.1016/j.bmcl.2013.05.016 | BV-2 | 3 |
| 23726032 | 10.1016/j.bmcl.2013.05.016 | PC-12 | 1 |
| 23726032 | 10.1016/j.bmcl.2013.05.016 | Radical scavenging activity | 1 |
Data from ChEMBL 36 via Core Engine