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Compound Detail

CHEMBL24238

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C[C@@](N)(C(=O)O)c1ccc(C(=O)O)cc1.N[C@@H](Cn1oc(=O)[nH]c1=O)C(=O)O

Basic Information

ChEMBL ID CHEMBL24238
Phase Preclinical
Structure Type MOL
InChI Key IPEKMHKTSANKJT-GBZGCGEDSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

398.3
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H18N4O9
MW 398.33

Activity Summary

EC50 2 meas. best 6.2

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Rattus norvegicus
CHEMBL376
EC50 6.2 6.035 630.0 2

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9871639 10.1016/s0960-894x(97)10208-6 Rattus norvegicus 4

Data from ChEMBL 36 via Core Engine