Assay Detail
Functional
CHEMBL783113
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Effective concentration by measuring IP1 accumulation using rat fore brain synaptoneurosomes
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of glutamic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.85 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279956 | QUISQUALATE | — | 1 | 7.00 |
| CHEMBL24846 | — | — | 1 | 6.85 |
| CHEMBL24238 | — | — | 1 | 6.20 |
| CHEMBL34453 | — | — | 1 | 4.77 |
| CHEMBL1159885 | — | — | 1 | 4.43 |
| CHEMBL1159884 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279956 | QUISQUALATE | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL24846 | — | EC50 | = | 140.0 | nM | 6.85 |
| CHEMBL24238 | — | EC50 | = | 630.0 | nM | 6.20 |
| CHEMBL34453 | — | EC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL1159885 | — | EC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL1159884 | — | EC50 | = | 109000.0 | nM | - |