Compound Detail
CHEMBL24846
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N[C@@H](CC(C=O)CCCCN1C(=O)c2ccccc2C1=O)C(=O)O.N[C@@H](Cn1oc(=O)[nH]c1=O)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL24846 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ODWMLXLGVIUYDB-NQNITNEUSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
521.5
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | EC50 | 6.85 | 6.71 | 140.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | EC50 | = | 140.0 | nM | 6.85 | Effective concentration by measuring IP1 accumulation using rat fore brain synap... | 9871639 |
| Rattus norvegicus | EC50 | = | 270.0 | nM | 6.57 | Effective concentration by measuring IP2 accumulation using rat fore brain synap... | 9871639 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9871639 | 10.1016/s0960-894x(97)10208-6 | Rattus norvegicus | 4 |
Data from ChEMBL 36 via Core Engine