Compound Detail
CHEMBL247716
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Basic Information
| ChEMBL ID | CHEMBL247716 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IDAXMZPAWQFAEJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
336.3
MW (Da)
3.04
ALogP
4
HBA
2
HBD
53.9
PSA (Ų)
0.91
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2B CHEMBL1904 | Ki | 5.13 | 5.13 | 7350.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2B | Ki | = | 7350.0 | nM | 5.13 | Binding affinity to NMDA NR2B receptor | 17498948 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17498948 | 10.1016/j.bmcl.2007.04.084 | Glutamate receptor ionotropic, NMDA 2B | 1 |
Data from ChEMBL 36 via Core Engine