Compound Detail
CHEMBL256608
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL256608 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AEBRINKRALSWNY-BYPYZUCNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
117.2
MW (Da)
0.06
ALogP
2
HBA
2
HBD
63.3
PSA (Ų)
0.55
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit rho-1 CHEMBL3561 | EC50 | 4.19 | 4.19 | 65000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit rho-1 | EC50 | = | 65000.0 | nM | 4.19 | Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus l... | 17981464 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17981464 | 10.1016/j.bmcl.2007.10.019 | Gamma-aminobutyric acid receptor subunit rho-1 | 1 |
Data from ChEMBL 36 via Core Engine