Compound Detail
CHEMBL26418
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Basic Information
| ChEMBL ID | CHEMBL26418 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ARUQPLWGHMJTRI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
146.2
MW (Da)
-0.99
ALogP
4
HBA
3
HBD
67.5
PSA (Ų)
0.26
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ornithine decarboxylase CHEMBL3511 | IC50 | 4.68 | 4.68 | 21000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ornithine decarboxylase | IC50 | = | 21000.0 | nM | 4.68 | Inhibitory activity against Rat liver ornithine decarboxylase (ODC) | 1573631 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1573631 | 10.1021/jm00086a003 | Ornithine decarboxylase | 1 |
| 1573631 | 10.1021/jm00086a003 | T-24 | 1 |
Data from ChEMBL 36 via Core Engine