Compound Detail
CHEMBL268269
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Basic Information
| ChEMBL ID | CHEMBL268269 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBBQEJISIMWYOF-XYOKQWHBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
452.5
MW (Da)
3.93
ALogP
8
HBA
2
HBD
118.8
PSA (Ų)
0.28
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cavia porcellus CHEMBL369 | IC50 | 6.72 | 6.72 | 190.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cavia porcellus | IC50 | = | 190.0 | nM | 6.72 | Inhibition of LTD4 induced contraction of guinea pig ileum | 9089329 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9089329 | 10.1021/jm960628d | Cysteinyl leukotriene receptor 1 | 1 |
| 9089329 | 10.1021/jm960628d | Cavia porcellus | 1 |
Data from ChEMBL 36 via Core Engine