Compound Detail
CHEMBL269157
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL269157 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GCEOZHFFNHJZTB-VKAVYKQESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
300.3
MW (Da)
2.59
ALogP
5
HBA
0
HBD
91.8
PSA (Ų)
0.28
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 7.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cavia porcellus CHEMBL369 | EC50 | 7.29 | 7.29 | 51.3 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cavia porcellus | EC50 | = | 51.29 | nM | 7.29 | Inhibition of spontaneous tone in guinea pig trachaelis | - |
| Cavia porcellus | EC50 | = | 51.29 | nM | 7.29 | Tested for the ability to inhibit spontaneous tone in guinea pig trachealis by 5... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80551-5 | Rattus norvegicus | 2 |
| - | 10.1016/S0960-894X(01)80551-5 | Cavia porcellus | 2 |
| - | 10.1016/S0960-894X(00)80297-8 | Cavia porcellus | 2 |
| - | 10.1016/S0960-894X(00)80297-8 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine