Compound Detail
CHEMBL274552
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Basic Information
| ChEMBL ID | CHEMBL274552 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PSWIYSNTEKDWMQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
441.4
MW (Da)
4.04
ALogP
3
HBA
1
HBD
49.4
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor CHEMBL1907609 | IC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor | IC50 | = | 500.0 | nM | 6.3 | Displacement of [3H]N-methylscopolamine from rat brain homogenate | 2785211 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2785211 | 10.1021/jm00125a021 | Muscarinic acetylcholine receptor | 1 |
Data from ChEMBL 36 via Core Engine