Compound Detail
CHEMBL278009
PTERINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL278009 |
| Name | PTERINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HNXQXTQTPAJEJL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
3
Known Names
Molecular Properties
163.1
MW (Da)
-0.70
ALogP
5
HBA
2
HBD
97.5
PSA (Ų)
0.53
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Queuine tRNA-ribosyltransferase CHEMBL2987 | Ki | 6.22 | 6.22 | 600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Queuine tRNA-ribosyltransferase | Ki | = | 600.0 | nM | 6.22 | Inhibitory activity against eubacterial tRNA guanine transglycosylase (TGT) from... | 12646024 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12646024 | 10.1021/jm0209937 | Queuine tRNA-ribosyltransferase | 1 |
Data from ChEMBL 36 via Core Engine