Compound Detail
CHEMBL279464
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Basic Information
| ChEMBL ID | CHEMBL279464 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | COIUOECSBDDSNQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
5.22
ALogP
4
HBA
1
HBD
64.7
PSA (Ų)
0.47
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Progesterone receptor CHEMBL208 | EC50 | 8.33 | 8.33 | 4.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Progesterone receptor | EC50 | = | 4.7 | nM | 8.33 | Effective concentration on alkaline phosphatase activity in human T47D breast ca... | 12657271 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12657271 | 10.1016/s0960-894x(03)00128-8 | Progesterone receptor | 1 |
Data from ChEMBL 36 via Core Engine