Compound Detail
CHEMBL281715
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL281715 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XCGQZVNCVNGBEC-HXUWFJFHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
459.6
MW (Da)
1.36
ALogP
6
HBA
3
HBD
120.5
PSA (Ų)
0.49
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prothrombin CHEMBL204 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prothrombin | Ki | = | 10000.0 | nM | 5.0 | Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degr... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)00210-2 | Prothrombin | 1 |
| - | 10.1016/S0960-894X(97)00210-2 | Serine protease 1 | 1 |
| - | 10.1016/S0960-894X(97)00210-2 | Plasminogen | 1 |
Data from ChEMBL 36 via Core Engine