Compound Detail
CHEMBL282656
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Basic Information
| ChEMBL ID | CHEMBL282656 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NXTJMIIQUAYQDI-YFBHCESUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
253.2
MW (Da)
-1.02
ALogP
4
HBA
5
HBD
127.1
PSA (Ų)
0.41
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.97
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 6.97 | 6.97 | 106.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 106.0 | nM | 6.97 | The compound was tested for NMDA antagonist activity against [3H]-CGS- 19755 bin... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80223-1 | Glutamate NMDA receptor | 1 |
Data from ChEMBL 36 via Core Engine