Compound Detail
CHEMBL284060
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Basic Information
| ChEMBL ID | CHEMBL284060 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MCAPGXLLTIUQQF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
274.4
MW (Da)
1.40
ALogP
3
HBA
2
HBD
66.6
PSA (Ų)
0.81
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mu-type opioid receptor CHEMBL4354 | IC50 | 5.21 | 5.21 | 6090.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mu-type opioid receptor | IC50 | = | 6090.0 | nM | 5.21 | Mu opioid receptor agonist activity as inhibition of electrically stimulated mys... | 7154002 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7154002 | 10.1021/jm00354a006 | Mu-type opioid receptor | 3 |
Data from ChEMBL 36 via Core Engine