Compound Detail
CHEMBL28797
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Basic Information
| ChEMBL ID | CHEMBL28797 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HAAKJHPJDSOUSI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
361.5
MW (Da)
5.60
ALogP
3
HBA
1
HBD
42.4
PSA (Ų)
0.62
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor 1 CHEMBL5645 | Ki | 5.17 | 5.17 | 6800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor 1 | Ki | = | 6800.0 | nM | 5.17 | Inhibition of [3H]LTD4 binding to LTD4 receptor in guinea pig lung membranes | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00225-I | Cysteinyl leukotriene receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine