Compound Detail
CHEMBL290997
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL290997 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OEKJNXNLPAEOIY-WHUSZIJCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
413.6
MW (Da)
7.61
ALogP
5
HBA
0
HBD
60.5
PSA (Ų)
0.12
QED
1
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | Ki | 5.35 | 5.35 | 4500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | Ki | = | 4500.0 | nM | 5.35 | Inhibitory activity against fatty acid amide hydrolase (FAAH) | 11412972 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11412972 | 10.1016/s0960-894x(01)00211-6 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine