Compound Detail
CHEMBL293278
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Basic Information
| ChEMBL ID | CHEMBL293278 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RKCXCQAZSOBASC-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
372.5
MW (Da)
3.69
ALogP
6
HBA
1
HBD
77.1
PSA (Ų)
0.61
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| rhinovirus A2 CHEMBL612678 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
| Poliovirus 2 CHEMBL613752 | IC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| rhinovirus A2 | IC50 | = | 900.0 | nM | 6.05 | Antiviral activity against Human rhinovirus A2 | 31226653 |
| Poliovirus 2 | IC50 | = | 900.0 | nM | 6.05 | Antiviral activity against Human poliovirus 2 | 31226653 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2999407 | 10.1021/jm00150a025 | Mus musculus | 2 |
| 2999407 | 10.1021/jm00150a025 | Enterovirus | 1 |
| 31226653 | 10.1016/j.ejmech.2019.06.008 | rhinovirus A2 | 1 |
| 31226653 | 10.1016/j.ejmech.2019.06.008 | Poliovirus 2 | 1 |
Data from ChEMBL 36 via Core Engine