Compound Detail
CHEMBL307113
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Basic Information
| ChEMBL ID | CHEMBL307113 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NDTNWLZCHFUWIS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
247.4
MW (Da)
4.17
ALogP
2
HBA
0
HBD
3.2
PSA (Ų)
0.71
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2C CHEMBL401 | Ki | 7.92 | 7.92 | 12.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2C | Ki | = | 12.0 | nM | 7.92 | Ability to displace [3H]TCP from PCP receptor in tissue homogenate preparation o... | 2374147 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2374147 | 10.1021/jm00170a027 | Glutamate receptor ionotropic, NMDA 2C | 1 |
| 2374147 | 10.1021/jm00170a027 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine