Compound Detail
CHEMBL3088159
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Basic Information
| ChEMBL ID | CHEMBL3088159 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VNTMIVFMVGTSHV-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
219.4
MW (Da)
3.33
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.66
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Matrix protein 2 CHEMBL2052 | IC50 | 6.52 | 6.52 | 300.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.72 | 4.72 | 19000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Matrix protein 2 | IC50 | = | 300.0 | nM | 6.52 | Inhibition of Influenza A virus M2 ion channel V27A mutant by two-electrode volt... | 24237039 |
| Unchecked | IC50 | = | 19000.0 | nM | 4.72 | Inhibition of Influenza A virus M2 ion channel by two-electrode voltage clamp as... | 24237039 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24237039 | 10.1021/jm401340p | Matrix protein 2 | 2 |
| 24237039 | 10.1021/jm401340p | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine