Compound Detail
CHEMBL30919
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Basic Information
| ChEMBL ID | CHEMBL30919 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VOTOZHKAYLGZKY-FYYLOGMGSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
420.6
MW (Da)
4.47
ALogP
3
HBA
2
HBD
64.7
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gastrin/cholecystokinin type B receptor CHEMBL298 | IC50 | 8.16 | 8.16 | 6.9 | 1 |
| Cholecystokinin receptor type A CHEMBL2871 | IC50 | 6.19 | 6.19 | 646.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gastrin/cholecystokinin type B receptor | IC50 | = | 6.9 | nM | 8.16 | Inhibitory activity against Cholecystokinin type B receptor in guinea pig cerebr... | - |
| Cholecystokinin receptor type A | IC50 | = | 646.0 | nM | 6.19 | Inhibitory activity against Cholecystokinin type A receptor in rat pancreas usin... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00234-K | Cholecystokinin receptor type A | 1 |
| - | 10.1016/0960-894X(95)00234-K | Gastrin/cholecystokinin type B receptor | 1 |
| - | 10.1016/0960-894X(95)00234-K | Cholecystokinin receptor | 1 |
Data from ChEMBL 36 via Core Engine