Compound Detail
CHEMBL311283
CORREOLIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL311283 |
| Name | CORREOLIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VKDXHXWBOARFPD-GMNMBZFNSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
788.8
MW (Da)
2.45
ALogP
16
HBA
1
HBD
216.9
PSA (Ų)
0.17
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.52
Kd 1 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 3 CHEMBL4633 | Kd | 7.0 | 7.0 | 100.0 | 1 |
| Homo sapiens CHEMBL372 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 3 | Kd | = | 100.0 | nM | 7.0 | Dissociation constant for the blockage of voltage-gated potassium channel subuni... | 15084131 |
| Homo sapiens | EC50 | = | 300.0 | nM | 6.52 | Inhibition of anti-CD3 dependent human T cell proliferation | 15084131 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15084131 | 10.1021/jm030523s | Potassium voltage-gated channel subfamily A member 3 | 1 |
| 15084131 | 10.1021/jm030523s | Homo sapiens | 1 |
Data from ChEMBL 36 via Core Engine