Compound Detail
CHEMBL3126517
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Basic Information
| ChEMBL ID | CHEMBL3126517 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XRYBWRQEIBZBCX-YRNVUSSQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
394.1
MW (Da)
4.87
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.65
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Amyloid-beta precursor protein CHEMBL2487 | Ki | 6.84 | 6.84 | 143.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Ki | = | 143.81 | nM | 6.84 | Displacement of [125I]IMPY from amyloid beta (1 to 40) (unknown origin) after 2 ... | 24583352 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24583352 | 10.1016/j.ejmech.2014.02.020 | Amyloid-beta precursor protein | 1 |
Data from ChEMBL 36 via Core Engine