Compound Detail
CHEMBL3134121
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Basic Information
| ChEMBL ID | CHEMBL3134121 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SFJFWWCABWHCLD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
392.2
MW (Da)
3.47
ALogP
5
HBA
0
HBD
55.0
PSA (Ų)
0.64
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.87
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Amyloid-beta precursor protein CHEMBL2487 | Ki | 7.87 | 7.87 | 13.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Ki | = | 13.6 | nM | 7.87 | Inhibition of [125I]IMPY binding to amyloid beta (1 to 42) aggregates (unknown o... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C3MD00189J | Amyloid-beta precursor protein | 2 |
| - | 10.1039/C3MD00189J | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine