Compound Detail
CHEMBL313458
CARSATRIN 🧪 Phase II
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🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL313458 |
| Name | CARSATRIN |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | JOMBZLFCXNSKEQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
3
Known Names
Molecular Properties
496.6
MW (Da)
3.49
ALogP
7
HBA
2
HBD
81.2
PSA (Ų)
0.29
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Activity Summary
EC50 2 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.52 | 6.08 | 300.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 300.0 | nM | 6.52 | Relative change in CF was determined by calculating the effective concentration ... | 1335073 |
| Unchecked | EC50 | = | 2310.0 | nM | 5.64 | Effective concentration against Xenopus oocytes expressing human heart Na channe... | 7629798 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1335073 | 10.1021/jm00102a001 | Canis familiaris | 5 |
| 7629798 | 10.1021/jm00014a011 | Unchecked | 3 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 1335073 | 10.1021/jm00102a001 | NON-PROTEIN TARGET | 1 |
| 1335073 | 10.1021/jm00102a001 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine