Compound Detail
CHEMBL3142769
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCc1c[nH]c(=O)n([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O
Basic Information
| ChEMBL ID | CHEMBL3142769 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JFKOEBHLWIQYBL-XDSPWSPCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
603.9
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MT4 CHEMBL388 | EC50 | 7.18 | 7.18 | 66.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MT4 | EC50 | = | 66.0 | nM | 7.18 | Concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cells by 5... | 1501224 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1501224 | 10.1021/jm00094a009 | MT4 | 2 |
| 1501224 | 10.1021/jm00094a009 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine