Compound Detail
CHEMBL3143162
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3143162 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OCHGSLPHQSRFSL-XUVXKRRUSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
406.5
MW (Da)
3.70
ALogP
7
HBA
2
HBD
97.7
PSA (Ų)
0.52
QED
0
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 3 CHEMBL613132 | EC50 | 6.3 | 6.3 | 500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 3 | EC50 | = | 500.0 | nM | 6.3 | Compound was evaluated for the inhibition of VZV strains of OKA | 10579812 |
| Human alphaherpesvirus 3 | EC50 | = | 500.0 | nM | 6.3 | Compound was evaluated for the inhibition of VZV strains of YS | 10579812 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10579812 | 10.1021/jm990346o | Human alphaherpesvirus 3 | 4 |
| 10579812 | 10.1021/jm990346o | HEL | 2 |
Data from ChEMBL 36 via Core Engine