Compound Detail
CHEMBL3143184
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Basic Information
| ChEMBL ID | CHEMBL3143184 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OUYTYINYBMFKOA-RCCFBDPRSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
457.4
MW (Da)
2.04
ALogP
6
HBA
3
HBD
104.5
PSA (Ų)
0.28
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 3 CHEMBL613132 | EC50 | 6.1 | 5.615 | 800.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 3 | EC50 | = | 800.0 | nM | 6.1 | The compound was tested for its effective concentration required to reduce virus... | 10866384 |
| Human alphaherpesvirus 3 | EC50 | = | 1100.0 | nM | 5.96 | The compound was tested for its effective concentration required to reduce virus... | 10866384 |
| Human alphaherpesvirus 3 | EC50 | = | 2500.0 | nM | 5.6 | The compound was tested for its effective concentration required to reduce virus... | 10866384 |
| Human alphaherpesvirus 3 | EC50 | = | 16000.0 | nM | 4.8 | The compound was tested for its effective concentration required to reduce virus... | 10866384 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10866384 | 10.1016/s0960-894x(00)00193-1 | Human alphaherpesvirus 3 | 4 |
| 10866384 | 10.1016/s0960-894x(00)00193-1 | NON-PROTEIN TARGET | 1 |
| 10866384 | 10.1016/s0960-894x(00)00193-1 | HEL | 1 |
Data from ChEMBL 36 via Core Engine