Compound Detail

CHEMBL3181947

BROMFENAC SODIUM

💊 Approved Drug

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💊 Approved Drug

Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.O.O.O.[Na+].[Na+]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL3181947
Name	BROMFENAC SODIUM
Phase	Approved
Structure Type	MOL
InChI Key	PPOSVVJOVKVBPW-UHFFFAOYSA-L
Therapeutic	✓ Yes
Parent Compound	CHEMBL1077
Active Moiety	CHEMBL1077

Known Names

AHR-10282B Bromday Bromfenac monosodium salt Bromfenac monosodium salt sesquihydrate Bromfenac sodium Bromfenac sodium hydrate Bromfenac sodium sesquihydrate Bromsite Prolensa Xibrom Yellox

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Indications

Mechanisms

Molecular Properties

334.2

MW (Da)

2.89

ALogP

HBA

HBD

80.4

PSA (Å²)

0.67

QED

Ro5 Violations

Rot. Bonds

Drug Information

Molecule Type	Small molecule
First Approval	1997
Availability	Prescription
Chirality	Achiral

Routes of Administration

Topical

Flags

Withdrawn

USAN Stem	-ac
USAN Year	1986

Extended Properties

Molecular Formula	C30H28Br2N2Na2O9
MW	766.35
Aromatic Rings	2
Heavy Atoms	20
NP-Likeness	-0.41

Mechanism of Action

Mechanism	Action Type	Target	Direct	Efficacy
Cyclooxygenase inhibitor	INHIBITOR	Cyclooxygenase	✓	✓

Indications

Cataract Eye Pain Inflammation Ophthalmologic Surgical Procedures Pain, Postoperative

Drug Warnings

Withdrawn

drug misuse

Severe hepatitis and liver failure (some requiring transplantation); Hepatic Failure; Off-Label Abuse