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Compound Detail

CHEMBL3210329

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CCCCN(CC)S(=O)(=O)c1ccc(C(=O)/N=c2\sc3cc(NC(C)=O)ccc3n2C)cc1

Basic Information

ChEMBL ID CHEMBL3210329
Phase Preclinical
Structure Type MOL
InChI Key WRMHRTIQPOFKSI-BZZOAKBMSA-N
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

488.6
MW (Da)
3.75
ALogP
6
HBA
1
HBD
100.8
PSA (Ų)
0.52
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H28N4O4S2
MW 488.64
Aromatic Rings 3
Heavy Atoms 33
NP-Likeness -2.42

Activity Summary

EC50 4 meas. best 5.28

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 5.28 5.0775 5230.0 4

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine