Compound Detail
CHEMBL3217942
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Basic Information
| ChEMBL ID | CHEMBL3217942 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XFDDBQQVCVLOPJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
386.4
MW (Da)
5.17
ALogP
5
HBA
0
HBD
47.7
PSA (Ų)
0.47
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL2243 | IC50 | 7.89 | 7.89 | 13.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 13.0 | nM | 7.89 | Inhibition of human FAAH expressed in HEK293 cells using arachadonyl 7-amino 4-m... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C2MD00307D | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine