Compound Detail
CHEMBL322088
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL322088 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HODJFSFDQRCCAY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
208.3
MW (Da)
2.11
ALogP
4
HBA
0
HBD
34.9
PSA (Ų)
0.76
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium-transporting ATPase CHEMBL2095228 | IC50 | 6.28 | 6.28 | 530.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium-transporting ATPase | IC50 | = | 530.0 | nM | 6.28 | Inhibition of porcine gastric H+/K+ ATPase | 9022797 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9022797 | 10.1021/jm9605593 | Potassium-transporting ATPase | 1 |
Data from ChEMBL 36 via Core Engine