Compound Detail
CHEMBL3235706
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Basic Information
| ChEMBL ID | CHEMBL3235706 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YBMSMYKJMQQYGZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
398.6
MW (Da)
6.19
ALogP
5
HBA
1
HBD
41.0
PSA (Ų)
0.51
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.61
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | IC50 | 6.61 | 6.61 | 245.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | IC50 | = | 245.47 | nM | 6.61 | Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293... | 24675175 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24675175 | 10.1016/j.ejmech.2014.03.040 | Corticotropin-releasing factor receptor 1 | 2 |
Data from ChEMBL 36 via Core Engine