Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3247309

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C/C=C\c1ccc(OCC(O)CNC(C)C)c(OC)c1

Basic Information

ChEMBL ID CHEMBL3247309
Phase Preclinical
Structure Type MOL
InChI Key GLPBNWPRXQKSNJ-WAYWQWQTSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

279.4
MW (Da)
2.47
ALogP
4
HBA
2
HBD
50.7
PSA (Ų)
0.77
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H25NO3
MW 279.38
Aromatic Rings 1
Heavy Atoms 20
NP-Likeness 0.08

Activity Summary

Kd 2 meas. best 7.7

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Beta-2 adrenergic receptor
CHEMBL3754
Kd 7.7 7.7 19.9 1
Beta-1 adrenergic receptor
CHEMBL3252
Kd 6.7 6.7 199.5 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
31488 10.1021/jm00207a025 Beta-1 adrenergic receptor 1
31488 10.1021/jm00207a025 Beta-2 adrenergic receptor 1
31488 10.1021/jm00207a025 Unchecked 1

Data from ChEMBL 36 via Core Engine