Compound Detail
CHEMBL326215
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Basic Information
| ChEMBL ID | CHEMBL326215 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DYVAJHXKMLPJCP-LNVKXUELSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
431.6
MW (Da)
4.67
ALogP
7
HBA
1
HBD
77.3
PSA (Ų)
0.28
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL5136 | Ki | 5.68 | 5.68 | 2092.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | Ki | = | 2092.0 | nM | 5.68 | Tested for inhibition of [3H]PAF binding to rabbit Platelet activating factor re... | 2175357 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2175357 | 10.1021/jm00174a017 | Platelet-activating factor receptor | 3 |
| 2175357 | 10.1021/jm00174a017 | Rattus norvegicus | 2 |
Data from ChEMBL 36 via Core Engine