Compound Detail
CHEMBL3262878
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Basic Information
| ChEMBL ID | CHEMBL3262878 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OZFSNYWIRVFTSZ-UHFFFAOYSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.5
MW (Da)
2.60
ALogP
3
HBA
0
HBD
49.9
PSA (Ų)
0.82
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 5.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| G-protein coupled receptor 183 CHEMBL3259470 | IC50 | 5.53 | 5.53 | 2934.0 | 2 |
| G-protein coupled receptor 183 CHEMBL3259471 | IC50 | 5.36 | 5.36 | 4341.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| G-protein coupled receptor 183 | IC50 | = | 2934.0 | nM | 5.53 | Antagonist activity at recombinant human EBI2 receptor expressed in CHO cells as... | 24678947 |
| G-protein coupled receptor 183 | IC50 | = | 2951.21 | nM | 5.53 | Antagonist activity at recombinant human EBI2 receptor expressed in CHO cells as... | 24678947 |
| G-protein coupled receptor 183 | IC50 | = | 4341.0 | nM | 5.36 | Antagonist activity at recombinant mouse EBI2 receptor expressed in CHO cells as... | 24678947 |
| G-protein coupled receptor 183 | IC50 | = | 4365.16 | nM | 5.36 | Antagonist activity at recombinant mouse EBI2 receptor expressed in CHO cells as... | 24678947 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24678947 | 10.1021/jm4019355 | G-protein coupled receptor 183 | 4 |
Data from ChEMBL 36 via Core Engine