Compound Detail
CHEMBL3288283
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3288283 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AETRMEAALJJLHQ-UHFFFAOYSA-N |
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
207.4
MW (Da)
3.33
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.75
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 5 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Influenza A virus CHEMBL613740 | EC50 | 6.52 | 5.9133 | 300.0 | 3 |
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 5.07 | 5.07 | 8500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Influenza A virus | EC50 | = | 300.0 | nM | 6.52 | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected... | 24793875 |
| Influenza A virus | EC50 | = | 1500.0 | nM | 5.82 | Antiviral activity against Influenza A virus A2/Taiwan/1/64(H2N2) infected in MD... | 24793875 |
| Influenza A virus | EC50 | = | 4000.0 | nM | 5.4 | Antiviral activity against Influenza A virus A/Victoria/3/75(H3N2) infected in M... | 24793875 |
| NON-PROTEIN TARGET | EC50 | = | 8500.0 | nM | 5.07 | Antiviral activity against Influenza A virus (A/California/07/2009(H1N1)) infect... | 24793875 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24793875 | 10.1021/jm500598u | Influenza A virus | 4 |
| 24793875 | 10.1021/jm500598u | NON-PROTEIN TARGET | 1 |
| 24793875 | 10.1021/jm500598u | MDCK | 1 |
Data from ChEMBL 36 via Core Engine