Compound Detail
CHEMBL3310836
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3310836 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SLRBDYYHLWNXHF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
462.3
MW (Da)
1.97
ALogP
7
HBA
4
HBD
133.7
PSA (Ų)
0.42
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| C-C chemokine receptor type 4 CHEMBL2414 | IC50 | 5.8 | 5.8 | 1584.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| C-C chemokine receptor type 4 | IC50 | = | 1584.89 | nM | 5.8 | Antagonist activity at human CCR4 expressed in CHO cell membranes by [35S]-GTPga... | 24909677 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24909677 | 10.1016/j.bmc.2014.05.021 | C-C chemokine receptor type 4 | 2 |
| 24909677 | 10.1016/j.bmc.2014.05.021 | No relevant target | 2 |
Data from ChEMBL 36 via Core Engine