Compound Detail
CHEMBL3314371
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COCc1c(OC(C)=O)c(-c2ccc(O[Si](C)(C)C(C)(C)C)cc2)c(COC)c(OC(C)=O)c1-c1ccc(O[Si](C)(C)C(C)(C)C)cc1
Basic Information
| ChEMBL ID | CHEMBL3314371 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DYIXJVRWJITQPD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
695.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 4.72 | 4.72 | 19100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 19100.0 | nM | 4.72 | Cytotoxicity against human HL60 cells after 48 hrs by MTT assay | 24948566 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24948566 | 10.1016/j.bmcl.2014.05.091 | NON-PROTEIN TARGET | 1 |
| 24948566 | 10.1016/j.bmcl.2014.05.091 | Prolyl endopeptidase | 1 |
Data from ChEMBL 36 via Core Engine