Compound Detail
CHEMBL332341
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL332341 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBCGBKICSXVWQM-VMPITWQZSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
320.4
MW (Da)
3.03
ALogP
4
HBA
1
HBD
59.3
PSA (Ų)
0.94
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 6.35 | 5.855 | 450.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 450.0 | nM | 6.35 | In vitro inhibition of collagen stimulated platelet aggregation in human thrombo... | 2536438 |
| Homo sapiens | IC50 | = | 1000.0 | nM | 6.0 | In vitro inhibition of collagen stimulated platelet aggregation in human whole b... | 2536438 |
| Homo sapiens | IC50 | = | 1700.0 | nM | 5.77 | In vitro inhibition of ADP stimulated platelet aggregation in human whole blood | 2536438 |
| Homo sapiens | IC50 | = | 5000.0 | nM | 5.3 | In vitro inhibition of ADP stimulated platelet aggregation in human thrombocyte ... | 2536438 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2536438 | 10.1021/jm00122a011 | Homo sapiens | 4 |
| 2536438 | 10.1021/jm00122a011 | Canis familiaris | 1 |
| 2536438 | 10.1021/jm00122a011 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine