Compound Detail
CHEMBL3325920
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Basic Information
| ChEMBL ID | CHEMBL3325920 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNDPGFKINLFTLJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
252.4
MW (Da)
2.89
ALogP
2
HBA
1
HBD
29.3
PSA (Ų)
0.79
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.23
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL2056 | Ki | 6.23 | 6.23 | 583.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 583.0 | nM | 6.23 | Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293... | 25076379 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25076379 | 10.1016/j.ejmech.2014.07.059 | D(1A) dopamine receptor | 1 |
| 25076379 | 10.1016/j.ejmech.2014.07.059 | D(2) dopamine receptor | 1 |
| 25076379 | 10.1016/j.ejmech.2014.07.059 | D(3) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine