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Compound Detail

CHEMBL3326852

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CCOc1c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c2c1=O

Basic Information

ChEMBL ID CHEMBL3326852
Phase Preclinical
Structure Type MOL
InChI Key DJPXWRPQEOTGRW-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names

Molecular Properties

330.3
MW (Da)
2.68
ALogP
7
HBA
4
HBD
120.4
PSA (Ų)
0.54
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H14O7
MW 330.29
Aromatic Rings 3
Heavy Atoms 24
NP-Likeness 1.24

Activity Summary

IC50 2 meas. best 6.41

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 6.41 6.41 390.0 1
DNA polymerase eta
CHEMBL5542
IC50 4.47 4.47 33500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine