Compound Detail
CHEMBL3331622
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Basic Information
| ChEMBL ID | CHEMBL3331622 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OZQRSDCVZYGMMZ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
361.3
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase CHEMBL1929 | IC50 | 8.53 | 8.53 | 3.0 | 1 |
| Xanthine dehydrogenase/oxidase CHEMBL3649 | IC50 | 7.88 | 7.88 | 13.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Xanthine dehydrogenase/oxidase | IC50 | = | 2.97 | nM | 8.53 | Inhibition Assay: The inhibition of the activity of xanthine oxidase (XO) is tes... | - |
| Xanthine dehydrogenase/oxidase | IC50 | = | 13.3 | nM | 7.88 | Inhibition of bovine xanthine oxidase assessed as inhibition of uric acid format... | 25113879 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25113879 | 10.1016/j.ejmech.2014.08.014 | Xanthine dehydrogenase/oxidase | 1 |
Data from ChEMBL 36 via Core Engine