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Compound Detail

CHEMBL3349504

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CC[C@@H](C)[C@H]1NC(=O)CC2(CCCCC2)SSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC1=O

Basic Information

ChEMBL ID CHEMBL3349504
Phase Preclinical
Structure Type MOL
InChI Key GEDADTLYAYNOHV-BLCDEMBQSA-N
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

1058.3
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C48H75N13O10S2
MW 1058.34

Activity Summary

Kd 5 meas. best 7.98

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Rattus norvegicus
CHEMBL376
Kd 7.98 7.328 10.5 5

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
7069720 10.1021/jm00346a016 Rattus norvegicus 8
7069720 10.1021/jm00346a016 Unchecked 4

Data from ChEMBL 36 via Core Engine