Compound Detail
CHEMBL335496
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Basic Information
| ChEMBL ID | CHEMBL335496 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YFTJRDXLHDIWOI-NETXQHHPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
182.2
MW (Da)
-0.15
ALogP
3
HBA
0
HBD
32.8
PSA (Ų)
0.52
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor CHEMBL1907609 | Ki | 8.4 | 8.4 | 4.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor | Ki | = | 4.0 | nM | 8.4 | Binding affinity against Muscarinic acetylcholine receptor using [3H]-OXO-M as t... | 9784090 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9784090 | 10.1021/jm980192x | Muscarinic acetylcholine receptor | 1 |
| 9784090 | 10.1021/jm980192x | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine