Compound Detail
CHEMBL3356812
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3356812 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DAXRGNVJSWALPI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
318.4
MW (Da)
4.39
ALogP
2
HBA
2
HBD
42.4
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 7.43 | 7.43 | 36.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 36.7 | nM | 7.43 | Displacement of [3H]TCP from rat brain NMDA receptor | 25499436 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25499436 | 10.1016/j.bmcl.2014.11.066 | Glutamate NMDA receptor | 2 |
Data from ChEMBL 36 via Core Engine