Compound Detail
CHEMBL3356817
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Basic Information
| ChEMBL ID | CHEMBL3356817 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MTNVKUHDSNVQQV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
317.4
MW (Da)
4.53
ALogP
2
HBA
2
HBD
56.2
PSA (Ų)
0.42
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 6.82 | 6.82 | 152.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 152.0 | nM | 6.82 | Displacement of [3H]TCP from rat brain NMDA receptor | 25499436 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25499436 | 10.1016/j.bmcl.2014.11.066 | Glutamate NMDA receptor | 2 |
Data from ChEMBL 36 via Core Engine