Compound Detail
CHEMBL336410
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
O=C(NCc1ccccc1)[C@H](Cc1c([Se][Se]c2[nH]c3ccccc3c2C[C@@H](NC(=O)C(F)(F)F)C(=O)NCc2ccccc2)[nH]c2ccccc12)NC(=O)C(F)(F)F
Basic Information
| ChEMBL ID | CHEMBL336410 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FWFCALLHZITRMJ-MEKGRNQZSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
934.7
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.21 | 5.21 | 6200.0 | 1 |
| Epidermal growth factor receptor CHEMBL203 | IC50 | 5.16 | 5.16 | 7000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 6200.0 | nM | 5.21 | Inhibition of Src tyrosine kinase | 9046331 |
| Epidermal growth factor receptor | IC50 | = | 7000.0 | nM | 5.16 | Inhibition of epidermal growth factor receptor (EGFr) | 9046331 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9046331 | 10.1021/jm960689b | Epidermal growth factor receptor | 1 |
| 9046331 | 10.1021/jm960689b | Platelet-derived growth factor receptor beta | 1 |
| 9046331 | 10.1021/jm960689b | Unchecked | 1 |
| 9046331 | 10.1021/jm960689b | NIH3T3 | 1 |
Data from ChEMBL 36 via Core Engine