Compound Detail
CHEMBL340152
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Basic Information
| ChEMBL ID | CHEMBL340152 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | PWJCWRKOASSUHL-GARJFASQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
299.4
MW (Da)
0.08
ALogP
4
HBA
3
HBD
112.7
PSA (Ų)
0.62
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Angiotensin-converting enzyme CHEMBL1808 | IC50 | 6.16 | 6.16 | 700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Angiotensin-converting enzyme | IC50 | = | 700.0 | nM | 6.16 | Inhibition against ACE. | 7966160 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7966160 | 10.1021/jm00049a019 | Angiotensin-converting enzyme | 1 |
Data from ChEMBL 36 via Core Engine